Asthme et Aspergillus

作者: C. Goyard , C. Godet

DOI: 10.1016/S1877-1203(15)30021-5

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摘要: Resume Il existe une association entre sensibilisation aux moisissures, infections fongiques non controlees et mauvais controle de l'asthme. Le diagnostic d'aspergillose bronchopulmonaire allergique (ABPA) repose sur trois criteres indispensables : la presence d'un trouble ventilatoire obstructif reversible ou mucoviscidose, un taux d'IgE totale >1000 Ul/ml specifiques Aspergillus > 0,35 KUA/l associes a deux parmi serologie aspergillaire positive, scanner evocateur d'ABPA eosinophilie sanguine >500 cellules/μmoL (en absence prise corticoides). traitement reduction l'inflammation locale par le recours corticoides systemiques diminution proliferation mycelienne lors des exacerbations prescription d'Itraconazole. La prevalence asthmes severes avec hypersensibilisation moisissures (SAFS) est d'environ 30 % azoles doit etre limite dans temps reserve situations refractaires maximaliste severes.

参考文章(6)
Alessandro C. PASQUALOTTO, Georgina POWELL, Robert NIVEN, David W. DENNING, The effects of antifungal therapy on severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis Respirology. ,vol. 14, pp. 1121- 1127 ,(2009) , 10.1111/J.1440-1843.2009.01640.X
David W. Denning, John E. Van Wye, Norman J. Lewiston, David A. Stevens, Adjunctive Therapy of Allergic Bronchopulmonary Aspergillosis with Itraconazole Chest. ,vol. 100, pp. 813- 819 ,(1991) , 10.1378/CHEST.100.3.813
David W Denning, Catherine Pashley, Domink Hartl, Andrew Wardlaw, Cendrine Godet, Stefano Del Giacco, Laurence Delhaes, Svetlana Sergejeva, Fungal allergy in asthma–state of the art and research needs Clinical and Translational Allergy. ,vol. 4, pp. 14- 14 ,(2014) , 10.1186/2045-7022-4-14
Ritesh Agarwal, Dheeraj Gupta, Ashutosh N. Aggarwal, Akshay K. Saxena, Arunaloke Chakrabarti, Surinder K. Jindal, Clinical Significance of Hyperattenuating Mucoid Impaction in Allergic Bronchopulmonary Aspergillosis Chest. ,vol. 132, pp. 1183- 1190 ,(2007) , 10.1378/CHEST.07-0808
David W. Denning, B. Ronan O'Driscoll, Georgina Powell, Fiona Chew, Graham T. Atherton, Aashish Vyas, John Miles, Julie Morris, Robert M. Niven, Randomized controlled trial of oral antifungal treatment for severe asthma with fungal sensitization: The Fungal Asthma Sensitization Trial (FAST) study. American Journal of Respiratory and Critical Care Medicine. ,vol. 179, pp. 11- 18 ,(2009) , 10.1164/RCCM.200805-737OC
R. Agarwal, A. Chakrabarti, A. Shah, D. Gupta, J. F. Meis, R. Guleria, R. Moss, D. W. Denning, , Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria Clinical & Experimental Allergy. ,vol. 43, pp. 850- 873 ,(2013) , 10.1111/CEA.12141