摘要: Iron is an essential nutrient that facilitates cell proliferation and growth. However, iron also has the capacity to engage in redox cycling free radical formation. Therefore, can contribute both tumour initiation growth; recent work shown a role microenvironment metastasis. Pathways of acquisition, efflux, storage regulation are all perturbed cancer, suggesting reprogramming metabolism central aspect survival. Signalling through hypoxia-inducible factor (HIF) WNT pathways may altered cancer. Targeting metabolic provide new tools for cancer prognosis therapy.
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