Guinea pig pancreatic polypeptide: Structure and pancreatic content
作者： J Eng , C.-G Huang , Y.-C.E Pan , J.D Hulmes , R.S Yalow
DOI: 10.1016/0196-9781(87)90181-1
关键词:
摘要: Abstract Guinea pig (GP) pancreatic polypeptide (PP) has been purified from an acid-alcohol extract of 6 GP pancreata by a series 3 HLPC steps. The sequence for PP as compared with that beef and human is shown: A P L E V Y G D T Q MA M R I N ML Beef Human In single pancreas weighing 2.4 g the total content was 1.0 nmol glucagon 61 nmol; in dog 35 385 81 nmol. relatively low consistent fact lacks ventral pancreas, region which found highest concentration. high reported earlier studies.
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sci-hub.se 参考文章(21)
W. W. Bromer, L. G. Sinn, A. Staub, Otto K. Behrens, THE AMINO ACID SEQUENCE OF GLUCAGON Journal of the American Chemical Society. ,vol. 78, pp. 3858- 3860 ,(1956) , 10.1021/JA01596A084
John E. Shively, Ursino Del Valle, Russell Blacher, David Hawke, Warren P. Levy, Menachem Rubinstein, Stanley Stein, Courtney McGregor, Joseph Tarnowski, Robert Bartlett, David Lee, Sidney Pestka, Microsequence analysis of peptides and proteins Analytical Biochemistry. ,vol. 126, pp. 318- 326 ,(1982) , 10.1016/0003-2697(82)90522-X
RONALD E. CHANCE, NANCY E. MOON, MELVIN G. JOHNSON, 33 – Human Pancreatic Polypeptide (HPP) and Bovine Pancreatic Polypeptide (BPP) Methods of Hormone Radioimmunoassay (Second Edition). pp. 657- 672 ,(1978) , 10.1016/B978-0-12-379260-0.50040-6
David Hawke, Pau-Miau Yuan, John E. Shively, Microsequence analysis of peptides and proteins: II. Separation of amino acid phenylthiohydantoin derivatives by high-performance liquid chromatography on octadecylsilane supports Analytical Biochemistry. ,vol. 120, pp. 302- 311 ,(1982) , 10.1016/0003-2697(82)90351-7
Arthur E. Zimmerman, Cecil C. Yip, Guinea pig insulin. I. Purification and physical properties. Journal of Biological Chemistry. ,vol. 249, pp. 4021- 4025 ,(1974) , 10.1016/S0021-9258(19)42477-0
W.W. Bromer, M.E. Boucher, J.E. Koffenberger, Amino Acid Sequence of Bovine Glucagon Journal of Biological Chemistry. ,vol. 246, pp. 2822- 2827 ,(1971) , 10.1016/S0021-9258(18)62256-2
G Heinrich, P Gros, J F Habener, Glucagon gene sequence. Four of six exons encode separate functional domains of rat pre-proglucagon. Journal of Biological Chemistry. ,vol. 259, pp. 14082- 14087 ,(1984) , 10.1016/S0021-9258(18)89859-3
R.M. Hewick, M.W. Hunkapiller, L.E. Hood, W.J. Dreyer, A gas-liquid solid phase peptide and protein sequenator. Journal of Biological Chemistry. ,vol. 256, pp. 7990- 7997 ,(1981) , 10.1016/S0021-9258(18)43377-7
William W. Bromer, Studies with glucagon analogs Metabolism-clinical and Experimental. ,vol. 25, pp. 1315- 1316 ,(1976) , 10.1016/S0026-0495(76)80130-8
F. Sundby, J. Markussen, W. Danho, Rabbit glucagon: isolation, crystallization and amino acid composition. Hormone and Metabolic Research. ,vol. 4, pp. 425- 425 ,(1972) , 10.1055/S-0028-1095723