Cardiac Cell Therapy — Mixed Results from Mixed Cells

作者: Anthony Rosenzweig

DOI: 10.1056/NEJME068172

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摘要: Despite substantial advances in treatment, ischemic cardiac injury and the ventricular dysfunction it can provoke remain major causes of morbidity mortality throughout world. The endogenous regenerative capacity heart appears inadequate to repair injured myocardium, leading cumulative loss cardiomyocytes over lifetime a patient. This may contribute prevalence failure as diagnosis at hospital admission — particularly among elderly. For these reasons, experiments animals suggesting that transfer cells derived from bone marrow (BMC) could dramatically improve function after infarction through regeneration myocardium . . .

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