Disparities in prevalence of key chronic diseases by gender and race/ethnicity among antiretroviral-treated HIV-infected adults in the US.

作者: Kate Buchacz , , Rose K Baker , Frank J Palella Jr , Lauren Shaw

DOI: 10.3851/IMP2450

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摘要: BACKGROUND Certain sociodemographic subgroups of HIV-infected patients may experience more chronic disease than others due to behavioural risk factors, advanced HIV or complications from extended use combination antiretroviral therapy (cART), but recent comparative data are limited. METHODS We studied adult in care during 2006-2010 who had been prescribed ≥ 6 months cART. analysed the prevalence selected key conditions and polymorbidity (having 2 out 10 conditions) by gender race/ethnicity. RESULTS Of 3,166 (median age 47 years, CD4⁺ T-cell count 496 cells/mm³, duration cART 6.8 years), 21% were female, 57% non-Hispanic White over half current former tobacco smokers. The five most frequent among women 45 years) dyslipidaemia (67.3%), hypertension (57.4%), obesity (31.7%), viral hepatitis B C coinfection (29.0%) low high-density lipoprotein cholesterol (HDLc; 27.3%). men (81.2%), (54.4%), HDLc (41.1%), elevated triglycerides (32.3%) non-HDLc (26.8%). In multivariable analyses, Hispanic higher diabetes patients; Black lower rates lipid abnormalities. all patients, 73.7% 66.8% polymorbidity, with no evidence disparities CONCLUSIONS Among contemporary cART-treated adults, common, underscoring importance prevention management ageing patients.

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