Malate salts, and polymorphs of (3s,5s)-7-[3-amino-5-methyl-piperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

作者: Nancy Lee Redman-Furey , Michael Lloyd Dicks , Jane Ellen Godlewski

DOI:

关键词:

摘要: The present invention is directed to malate salts of (3S,5S)-7-[3-amino-5-methyl- piperidinyl]-l-cyclopropyl-l,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid, and its polymorphs. also pharmaceutical compositions comprising the described

参考文章(108)
Junichi Mitsuyama, Kazuya Hayashi, Tetsumi Yamakawa, Hiroyo Kawafuchi, Tokunori Kito, Hiroshi Kuroda, Quinolonecarboxylic acid derivatives or salts thereof ,(1997)
Andrew Kenneth SmithKline Beecham Pharm. Takle, Roger Edward SmithKline Beecham Pharm. Markwell, David Thomas SmithKline Beecham Pharm. Davies, Neil David SmithKline Beecham Pharm. Pearson, Quinoline derivatives and their use as antibacterial agents ,(1999)
A. De Sarro, V. Cecchetti, V. Fravolini, F. Naccari, O. Tabarrini, G. De Sarro, Effects of Novel 6-Desfluoroquinolones and Classic Quinolones on Pentylenetetrazole-Induced Seizures in Mice Antimicrobial Agents and Chemotherapy. ,vol. 43, pp. 1729- 1736 ,(1999) , 10.1128/AAC.43.7.1729
Oriana Tabarrini, Claudia Sissi, Arnaldo Fravolini, Manlio Palumbo, 6-Hydroxy Derivative as New Desfluoroquinolone (DFQ): Synthesis and DNA-Binding Study Nucleosides, Nucleotides & Nucleic Acids. ,vol. 19, pp. 1327- 1336 ,(2000) , 10.1080/15257770008033055
Ronald Eugene White, Thomas Prosser Demuth, Antimicrobial quinolone thioureas ,(1991)
Seigo Suzue, Keiji Hirai, Takayoshi Ishizaki, Kuniyoshi Masuzawa, Quinolonecarboxylic acid derivatives ,(1986)
Yasuhiro Kuramoto, Yoshihiro Ohshita, Norihiro Hayashi, Yuzo Hirao, Shinobu Maruyama, Quinolone derivative or salt thereof, and antibacterial containing the same ,(1992)
Tetsushi Katsube, Tomio Kimura, Masayuki Iwata, Yoshimi Fujihara, Teruhiko Inoue, 4-oxoquinoline-3-carboxylic acid derivatives and their use ,(1990)
John Michael Domagala, Mark James Suto, William Richard Turner, Quinolinecarboxylic acid antibacterial agents ,(1991)
Akihiko Moriguchi, Yoshifumi Ikeda, Hideki Ao, Tsuyoshi Kuroda, Kazuyuki Kawasaki, Shin-ichi Uesato, 8-methoxy-quinolonecarboxylic acid derivatives ,(1995)