Combined Factors for Predicting Cognitive Impairment in Elderly Population Aged 75 Years and Older: From a Behavioral Perspective

摘要: To unravel the combined effect of risk and protective factors that may contribute to preserve or impair cognitive status, this prospective cohort study systematically investigated a cluster in elders aged 75 years older from Guangxi Longitudinal Cohort (GLC) dataset. GLC has tracked 630 oldest-elders for two times within 2 will continue follow next 4 years. At baseline geriatric assessment, sociodemographic information (e.g., education, Mandarin, marriage, income), physical status [body mass index (BMI), chronic disease/medicine], lifestyle (smoking, alcohol, exercise), self-rated mental health (self-care, well-being, anxiety) were recorded by online interview. With years' follow-up, Mini-Mental State Examination (MMSE) memory test performed through person-to-person The performance MMSE was applied represent responder's which classified into impairment normal group based on cutoff point 20. An age-related declining trend 15 stratified observed, though with small size (R-square: 0.001-0.15). odds exposure non-exposure (memory, self-care, exercise, income, literacy) had significantly different multivariate analysis after adjusting other confounding variables. Through stepwise multiple logistic regression analysis, following 12 factors/index would be integrated predict impairment: gender, (BMI, disease), socioeconomic (education, literacy, psychological self-care cognition, anxiety). Related clinical nursing applications also discussed.