In situ characterization of mononuclear cells in human dental periapical inflammatory lesions using monoclonal antibodies
作者： R. Nilsen , A.C. Johannessen , N. Skaug , R. Matre
DOI: 10.1016/0030-4220(84)90131-2
关键词:
摘要: Mononuclear cells in cryostat sections of human dental periapical inflammatory lesions were studied with the aid murine monoclonal antibodies and indirect immunofluorescence microscopy. T lymphocytes (OKT3-positive cells) made up a major part infiltrates. They found mainly clusters, although single also seen. helper (OKT4) more numerous than suppressor/cytotoxic (OKT8-positive cells), ratio approximately 2:1. Langerhans (OKT6-positive not demonstrated: only few scattered HNK 1-positive cells, probably natural killer detected. A large number OKM1- OKIa detected Their size varied considerably different areas sections. These are macrophages. Sheets small demonstrated, indicating presence B or activated lymphocytes. The results indicate that immune reactions may be importance pathogenesis lesions.
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