Pharmacological prevention of acute ventilatory capacity reduction in flax dust exposure.

摘要: Valic, F., and Žuskin, E. (1973).British Journal of Industrial Medicine,30, 381-384. Pharmacological prevention acute ventilatory capacity reduction in flax dust exposure. The protective effect the preshift application a bronchodilator (orciprenaline), an antihistamine drug (diadril), ascorbic acid on flax-induced bronchoconstriction was studied 13 byssinotic 7 non-byssinotic female workers exposed to airborne fibres biologically retted flax. Orciprenaline applied by inhalation, while diadril were given orally. All three drugs exerted significant preventive effect, diminishing fall during shift. forced expiratory volume (FEV1·0) reduced 50% maximal flow rate at vital (Vmax VC) over 65%.