Effects of caffeine and stress on biomarkers of cardiovascular disease in healthy men and women with a family history of hypertension.
作者： Jeanette M. Bennett , Isabella M. Rodrigues , Laura Cousino Klein
DOI: 10.1002/SMI.2486
关键词:
摘要: The connection between caffeine and its potentially detrimental effects on blood markers of cardiovascular disease (CVD) are controversial. Most studies have focused cholesterol as a putative mediator the caffeine–CVD relationship. Other such C-reactive protein (CRP) fibrinogen been understudied. We examined psychological stress these CVD in healthy, young men women with confirmed family history hypertension. A total 52 normotensive, healthy adults (26 26 women) aged 18–29 years (21.4 ± 0.3) participated laboratory session to examine reactivity following consumption. All participants had normal levels. Blood pressure (BP), heart rate, serum cortisol CRP plasma were collected. Men administered displayed an additional increase systolic BP response stressor (p < 0.05). Stress interacted sex alter cortisol, but not These results may shed light sex-specific pathways that associate CVD. Copyright © 2013 John Wiley & Sons, Ltd.
elsevier.com
sci-hub.se 参考文章(59)
D. E. Grobbee, A. A. A. Bak, Coffee, caffeine and hemostasis: a review. Netherlands Journal of Medicine. ,vol. 37, pp. 242- 246 ,(1990)
Isabella M Rodrigues, Laura C Klein, Boiled or Filtered Coffee? Effects of Coffee and Caffeine on Cholesterol, Fibrinogen and C-reactive Protein Toxicological Reviews. ,vol. 25, pp. 55- 69 ,(2006) , 10.2165/00139709-200625010-00004
J J F Belch, R N Clayton, M McLaren, Gwen Kennedy, M Akber, T A Elhadd, T A M Abdu, A Hill, R Neary, Influence of the hormonal changes during the normal menstrual cycle in healthy young women on soluble adhesion molecules, plasma homocysteine, free radical markers and lipoprotein fractions. International Angiology. ,vol. 22, pp. 222- 228 ,(2003)
T Chou, Wake up and smell the coffee. Caffeine, coffee, and the medical consequences. Western Journal of Medicine. ,vol. 157, pp. 544- 553 ,(1992)
William R. Lovallo, Jack D. Shepard, William A. Maish, Thomas L. Whitsett, Edward M. Hampton, Influence of Grapefruit Juice on Caffeine Pharmacokinetics and Pharmacodynamics Pharmacotherapy. ,vol. 16, pp. 1046- 1052 ,(1996) , 10.1002/J.1875-9114.1996.TB03031.X
Mahrukh K Ganapathi, Andrzej Mackiewicz, D Samols, A Brabenec, I Kushner, D Schultz, SI Hu, None, Induction of C-reactive protein by cytokines in human hepatoma cell lines is potentiated by caffeine. Biochemical Journal. ,vol. 269, pp. 41- 46 ,(1990) , 10.1042/BJ2690041
Terry R Hartley, William R Lovallo, Thomas L Whitsett, Cardiovascular Effects of Caffeine in Men and Women American Journal of Cardiology. ,vol. 93, pp. 1022- 1026 ,(2004) , 10.1016/J.AMJCARD.2003.12.057
D Robertson, D Wade, R Workman, R L Woosley, J A Oates, Tolerance to the humoral and hemodynamic effects of caffeine in man. Journal of Clinical Investigation. ,vol. 67, pp. 1111- 1117 ,(1981) , 10.1172/JCI110124
Brigitte M. Kudielka, Juliane Hellhammer, Dirk H. Hellhammer, Oliver T. Wolf, Karl-Martin Pirke, Enikö Varadi, Jürgen Pilz, Clemens Kirschbaum, Sex differences in endocrine and psychological responses to psychosocial stress in healthy elderly subjects and the impact of a 2-week dehydroepiandrosterone treatment. The Journal of Clinical Endocrinology and Metabolism. ,vol. 83, pp. 1756- 1761 ,(1998) , 10.1210/JCEM.83.5.4758
Megan M. Kelly, Audrey R. Tyrka, George M. Anderson, Lawrence H. Price, Linda L. Carpenter, Sex differences in emotional and physiological responses to the Trier Social Stress Test. Journal of Behavior Therapy and Experimental Psychiatry. ,vol. 39, pp. 87- 98 ,(2008) , 10.1016/J.JBTEP.2007.02.003