Xanthohumol exhibits anti-myeloma activity in vitro through inhibition of cell proliferation, induction of apoptosis via the ERK and JNK-dependent mechanism, and suppression of sIL-6R and VEGF production.

作者: Adrianna Sławińska-Brych , Barbara Zdzisińska , Arkadiusz Czerwonka , Magdalena Mizerska-Kowalska , Magdalena Dmoszyńska-Graniczka

DOI: 10.1016/J.BBAGEN.2019.08.001

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摘要: … reduction of BrdU incorporation into the DNA of dividing cells. In the RPMI8226 cell culture, significant inhibition … In the case of the U266 cells, a statistically significant effect was found at …

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