A review on Citrullus colocynthis Schrad.: from traditional Iranian medicine to modern phytotherapy.

作者: Roja Rahimi , Gholamreza Amin , Mohammad Reza Shams Ardekani

DOI: 10.1089/ACM.2011.0297

关键词:

摘要: Abstract Citrullus colocynthis Schrad. is an annual plant that grows in the south, center, and east areas of Iran. It recognized by different pharmacologic activities traditional Iranian medicine (TIM) (i.e., purgative, anti-inflammatory, antidiabetic, analgesic, hair growth–promoting, abortifacient, antiepileptic. Some these were confirmed modern phytotherapy. Adverse events such as colic, diarrhea, hematochezia, nephrosis, vomiting narrow therapeutic index cause herbalists to use this cautiously. If some points about TIM are considered, it may be possible produce more tolerable preparations from plant. In article, all aspects reviewed; also, medicinal properties declared for compared with those showed addition, opinions phytotherapy safety acceptable dosage discussed.

参考文章(23)
D Goldfain, A Lavergne, A Galian, L Chauveinc, F Prudhomme, Peculiar acute toxic colitis after ingestion of colocynth: a clinicopathological study of three cases. Gut. ,vol. 30, pp. 1412- 1418 ,(1989) , 10.1136/GUT.30.10.1412
Walid Sh. Qazan ., Motasem M. Almasad ., Haytham Daradka ., Short and long effects of Citrullus colocynthis L. on reproductive system and fertility in female Spague-Dawley rats. Pakistan Journal of Biological Sciences. ,vol. 10, pp. 2699- 2703 ,(2007) , 10.3923/PJBS.2007.2699.2703
Mohammad Reza Shams Ardekani, Roja Rahimi, Behjat Javadi, Leila Abdi, Mahnaz Khanavi, Relationship between Temperaments of Medicinal Plants and Their Major Chemical Compounds Journal of Traditional Chinese Medicine. ,vol. 31, pp. 27- 31 ,(2011) , 10.1016/S0254-6272(11)60006-X
Haytham Daradka ., Motasem M. Almasad ., Walid Sh. Qazan ., Nasser M. El-Banna ., Omar H. Samara ., Hypolipidaemic effects of Citrullus colocynthis L. in rabbits. Pakistan Journal of Biological Sciences. ,vol. 10, pp. 2768- 2771 ,(2007) , 10.3923/PJBS.2007.2768.2771
Monireh Torabi Rahvar, Mohsen Naseri, Nima Hosseni Jazani, Hamid Reza Khalkhali, Shahram Shahabi, Zuhair Muhammad Hassan, Mehdi Mahdavi, Mahya Dezfouli, Hot and Cold natures and some parameters of neuroendocrine and immune systems in traditional Iranian medicine: a preliminary study. Journal of Alternative and Complementary Medicine. ,vol. 14, pp. 147- 156 ,(2008) , 10.1089/ACM.2007.0693
Sunil Kumar, Dinesh Kumar, Kamal Saroha, Nidhan Singh, Bhoodev Vashishta, None, Antioxidant and free radical scavenging potential of Citrullus colocynthis (L.) Schrad. methanolic fruit extract Acta Pharmaceutica. ,vol. 58, pp. 215- 220 ,(2008) , 10.2478/V10007-008-0008-1
S.E.I. Adam, M.A. Al-Yahya, A.H. Al-Farhan, Response of Najdi sheep to oral administration of Citrullus colocynthis fruits, Nerium oleander leaves or their mixture. Small Ruminant Research. ,vol. 40, pp. 239- 244 ,(2001) , 10.1016/S0921-4488(01)00184-5
Tehila Tannin-Spitz, Shlomo Grossman, Sara Dovrat, Hugo E. Gottlieb, Margalit Bergman, Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells. Biochemical Pharmacology. ,vol. 73, pp. 56- 67 ,(2007) , 10.1016/J.BCP.2006.09.012
Astrid Barth, Dieter Müller, Katrin Dürrling, In vitro investigation of a standardized dried extract of Citrullus colocynthis on liver toxicity in adult rats Experimental and Toxicologic Pathology. ,vol. 54, pp. 223- 230 ,(2002) , 10.1078/0940-2993-00252