KRAS Mutation and Microsatellite Instability: Two Genetic Markers of Early Tumor Development That Influence the Prognosis of Colorectal Cancer
作者： Garrett M. Nash , Mark Gimbel , Alfred M. Cohen , Zhao-Shi Zeng , Mackevin I. Ndubuisi
DOI: 10.1245/S10434-009-0713-0
关键词:
摘要: Introduction We examined two genetic markers established early in colorectal tumor development, microsatellite instability (MSI) and mutation of the KRAS proto-oncogene, to see if these changes influence metastatic disease progression survival.
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