Human parvovirus B19 infection and unbalanced translocation in a case of hydrops fetalis

作者: Christine Willekes , Frans J. M. E. Roumen , Anne-Marie W. van Elsacker-Niele , Harro T. Weiland , Christl Vermey-Keers

DOI: 10.1002/PD.1970140307

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摘要: In a case of hydrops fetalis, serological examination showed recent maternal human parvovirus B19 infection. Amniocentesis revealed unique unbalanced translocation between chromosomes 3 and 11 the fetus. The mother proved to have balanced reciprocal 11. A grossly macerated hydropic male fetus was delivered with flat nose low implanted deformed ears. Histopathological nuclear inclusion bodies in fetal erythroid cells, confirming Parvovirus DNA demonstrated by situ hybridization nuclei heart muscle cells. Our finding two different disorders one illustrates importance complete evaluation every especially concerning counselling on outcome future pregnancies. infection will not recur due acquired immunity mother, whereas endanger

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