VEGFs, receptors and angiogenesis.
作者： Tanja Veikkola , Kari Alitalo
关键词:
摘要: Angiogenesis, the formation of new blood vessels from pre--existing ones, is central for both normal development and homeostasis as well in certain pathological conditions. The vascular endothelial growth factors (VEGFs) their receptors are prime regulators physiological angiogenesis. different VEGFs have overlapping but specific roles controlling vessels. VEGF transduce signals mediating cell proliferation, migration, organization into functional remodeling vessel network. In recent years, rapid progress has been made understanding receptor-ligand interactions that orchestrate neovascularization process.
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sci-hub.se 参考文章(101)
M. Detmar, A. M. Dvorak, L. F. Brown, H. F. Dvorak, Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. American Journal of Pathology. ,vol. 146, pp. 1029- 1039 ,(1995)
Terri Davis‐Smyth, Helen Chen, Jeanie Park, Leonard G Presta, Napoleone Ferrara, None, The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade. The EMBO Journal. ,vol. 15, pp. 4919- 4927 ,(1996) , 10.1002/J.1460-2075.1996.TB00872.X
Alitalo K, Maglione D, Aprelikova O, Viglietto G, Chou Jy, Ferraro Mg, Lei Kj, Del Vecchio S, Guerriero, Persico Mg, Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14. Oncogene. ,vol. 8, pp. 925- 931 ,(1993)
M. Haltia, K. Alitalo, T. Böhling, E. Hatva, M. G. Persico, J. Jääskeläinen, Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas. American Journal of Pathology. ,vol. 148, pp. 763- 775 ,(1996)
Erwin Tschachler, Michael Stürzl, Wolfgang Weninger, Luciana Masiello, Roberto Benelli, Adriana Albini, Emmanuelle Cornali, Christian Zietz, Georg Breier, Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma. American Journal of Pathology. ,vol. 149, pp. 1851- 1869 ,(1996)
M. C. Puri, J. Rossant, K. Alitalo, A. Bernstein, J. Partanen, THE RECEPTOR TYROSINE KINASE TIE IS REQUIRED FOR INTEGRITY AND SURVIVAL OF VASCULAR ENDOTHELIAL-CELLS The EMBO Journal. ,vol. 14, pp. 5884- 5891 ,(1995) , 10.1002/J.1460-2075.1995.TB00276.X
V. Joukov, K. Pajusola, A. Kaipainen, D. Chilov, I. Lahtinen, E. Kukk, O. Saksela, N. Kalkkinen, K. Alitalo, A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. The EMBO Journal. ,vol. 15, pp. 290- 298 ,(1996) , 10.1002/J.1460-2075.1996.TB00359.X
Liisa Pertovaara, Arja Kaipainen, Tuija Mustonen, Arto Orpana, Napoleone Ferrara, Olli Saksela, Kari Alitalo, None, Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells. Journal of Biological Chemistry. ,vol. 269, pp. 6271- 6274 ,(1994) , 10.1016/S0021-9258(17)37365-9
Michael S. Pepper, Roberto Montesano, Stefano J. Mandriota, Lelio Orci, Jean-Dominique Vassalli, Angiogenesis: a paradigm for balanced extracellular proteolysis during cell migration and morphogenesis. Enzyme and Protein. ,vol. 49, pp. 138- 162 ,(1996) , 10.1159/000468622
Georg Breier, Karl H. Plate, Werner Risau, Christine Kremer, Up-regulation of flk-1/vascular endothelial growth factor receptor 2 by its ligand in a cerebral slice culture system Cancer Research. ,vol. 57, pp. 3852- 3859 ,(1997)