TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value.
作者： Christophe Deben , Vanessa Deschoolmeester , Filip Lardon , Christian Rolfo , Patrick Pauwels
DOI: 10.1016/J.CRITREVONC.2015.11.019
关键词:
摘要: … In this review the known data on the role of p53 on prognosis and response to … cell lung cancer is summarized. The focus is on the presence of genetic alterations in the TP53 or MDM2 …
sci-hub.se 参考文章(88)
Qian Kong, Ping Li, Qiong Tian, Min-Wen Ha, Role of MDM2 T309G polymorphism in susceptibility and prognosis of nonsmall cell lung cancer: a meta-analysis. Genetic Testing and Molecular Biomarkers. ,vol. 18, pp. 357- 365 ,(2014) , 10.1089/GTMB.2013.0506
E Wattel, C Preudhomme, B Hecquet, M Vanrumbeke, B Quesnel, I Dervite, P Morel, P Fenaux, p53 Mutations Are Associated With Resistance to Chemotherapy and Short Survival in Hematologic Malignancies Blood. ,vol. 84, pp. 3148- 3157 ,(1994) , 10.1182/BLOOD.V84.9.3148.3148
Barbara G. Campling, Wafik S. El-Deiry, Clinical Implications of p53 Mutations in Lung Cancer Methods in molecular medicine. ,vol. 75, pp. 53- 77 ,(2003) , 10.1385/1-59259-324-0:53
N Mohell, J Alfredsson, Å Fransson, M Uustalu, S Byström, J Gullbo, A Hallberg, V J N Bykov, U Björklund, K G Wiman, APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells Cell Death and Disease. ,vol. 6, ,(2015) , 10.1038/CDDIS.2015.143
Liv B. Gansmo, Stian Knappskog, Pål Romundstad, Kristian Hveem, Lars Vatten, Per E. Lønning, Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon International Journal of Cancer. ,vol. 137, pp. 96- 103 ,(2015) , 10.1002/IJC.29358
Christophe Deben, An Wouters, Ken Op de Beeck, Jolien van Den Bossche, Julie Jacobs, Karen Zwaenepoel, Marc Peeters, Jan Van Meerbeeck, Filip Lardon, Christian Rolfo, Vanessa Deschoolmeester, Patrick Pauwels, The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer Oncotarget. ,vol. 6, pp. 22666- 22679 ,(2015) , 10.18632/ONCOTARGET.4433
J. T. Zilfou, S. W. Lowe, Tumor Suppressive Functions of p53 Cold Spring Harbor Perspectives in Biology. ,vol. 1, ,(2009) , 10.1101/CSHPERSPECT.A001883
Shoichi Mori, Genshi Ito, Noriyasu Usami, Hiromu Yoshioka, Yuichi Ueda, Yoshinori Kodama, Masahide Takahashi, Kwun M. Fong, Kaoru Shimokata, Yoshitaka Sekido, p53 apoptotic pathway molecules are frequently and simultaneously altered in nonsmall cell lung carcinoma. Cancer. ,vol. 100, pp. 1673- 1682 ,(2004) , 10.1002/CNCR.20164
Wen-Pin Chien, Ruey-Hong Wong, Ya-Wen Cheng, Chih-Yi Chen, Huei Lee, Associations of MDM2 SNP309, Transcriptional Activity, mRNA Expression, and Survival in Stage I Non-Small-Cell Lung Cancer Patients with Wild-Type p53 Tumors Annals of Surgical Oncology. ,vol. 17, pp. 1194- 1202 ,(2010) , 10.1245/S10434-009-0853-2
Zheng Hu, Xiang Li, Xincai Qu, Yungang He, Brian Z. Ring, Enmin Song, Li Su, Intron 3 16 bp duplication polymorphism of TP53 contributes to cancer susceptibility: a meta-analysis. Carcinogenesis. ,vol. 31, pp. 643- 647 ,(2010) , 10.1093/CARCIN/BGQ018