Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasis

作者: Daniela Gabbia , Arianna Dalla Pozza , Laura Albertoni , Roberta Lazzari , Giorgia Zigiotto

DOI: 10.3748/WJG.V23.I42.7519

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摘要: Pregnane X receptor and constitutive androstane modulate differently CYP3A-mediated metabolism in early- late-stage cholestasis

参考文章(42)
Ester Gonzalez-Sanchez, Delphine Firrincieli, Chantal Housset, Nicolas Chignard, Nuclear receptors in acute and chronic cholestasis. Digestive Diseases. ,vol. 33, pp. 357- 366 ,(2015) , 10.1159/000371688
E Bush, A Ghosal, P E Thomas, H Satoh, D Moore, Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450. Drug Metabolism and Disposition. ,vol. 24, pp. 940- 947 ,(1996)
Swetha Rudraiah, Xi Zhang, Li Wang, Nuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet? Annual Review of Pharmacology and Toxicology. ,vol. 56, pp. 605- 626 ,(2016) , 10.1146/ANNUREV-PHARMTOX-010715-103209
Peter J. Meier, James L. Boyer, Michael Trauner, Molecular Pathogenesis of Cholestasis ,(2012)
Rut M. Agüero, Cristian Favre, Emilio A. Rodriguez-Garay, Inhibitory effect of short-term bile duct ligation on hepatic cytochrome P450 of bile acid-depleted rats. Pathobiology. ,vol. 69, pp. 30- 35 ,(2001) , 10.1159/000048755
Eugene Hrycay, Dana Forrest, Lin Liu, Renxue Wang, Jenny Tai, Anand Deo, Victor Ling, Stelvio Bandiera, Hepatic bile acid metabolism and expression of cytochrome P450 and related enzymes are altered in Bsep −/− mice Molecular and Cellular Biochemistry. ,vol. 389, pp. 119- 132 ,(2014) , 10.1007/S11010-013-1933-Y
Emina Halilbasic, Anna Baghdasaryan, Michael Trauner, Nuclear Receptors as Drug Targets in Cholestatic Liver Diseases Clinics in Liver Disease. ,vol. 17, pp. 161- 189 ,(2013) , 10.1016/J.CLD.2012.12.001
Kamal Ishak, Amelia Baptista, Leonardo Bianchi, Francesco Callea, Jan De Groote, Fred Gudat, Helmut Denk, Valeer Desmet, Gerhard Korb, Roderick N.M. MacSween, M.James Phillips, Bernard G. Portmann, Hemming Poulsen, Peter J. Scheuer, Martin Schmid, Heribert Thaler, Histological grading and staging of chronic hepatitis. Journal of Hepatology. ,vol. 22, pp. 696- 699 ,(1995) , 10.1016/0168-8278(95)80226-6
Barbara Renga, Marco Migliorati, Andrea Mencarelli, Sabrina Cipriani, Claudio D'Amore, Eleonora Distrutti, Stefano Fiorucci, Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. ,vol. 1809, pp. 157- 165 ,(2011) , 10.1016/J.BBAGRM.2011.01.008