Outbreak of Candida tropicalis fungemia in a neonatal intensive care unit.

摘要: OBJECTIVE: To describe an outbreak of Candida tropicalis fungemia in a neonatal intensive care unit (NICU), to evaluate the risk factors associated with this infection and possible mode nosocomial transmission. DESIGN: Descriptive case-control study. PATIENTS AND METHODS: Surveillance cultures were taken from hospitalized patients, personnel, inanimate objects NICU. Six patients C (cases) compared culture-negative matched for duration exposure NICU (controls). RESULTS: During five-month period, was isolated 29 blood six premature infants. The same organism also fingernail samples ward housekeeper, who had mild onychomycosis, asymptomatic nurse. Other potential reservoirs not identified among all other infants or hospital environment. more likely have received larger number antibiotics (4.0 versus 1.8, P < 0.001) been subjected longer total parenteral nutrition (TPN) therapy (8.5 2.67 days, = 0.004) than controls. CONCLUSIONS: can be attributed period TPN administered patients. Analysis events suggests that may result cross-infection between staff