Molecular mechanisms of fission in echinoderms: Transcriptome analysis.

摘要: Echinoderms are capable of asexual reproduction by fission. An individual divides into parts due to changes in the strength connective tissue body wall. The structure and mechanisms variations its echinoderms remain poorly studied. analysis transcriptomes individuals during process fission provides a new opportunity understand mutability. In holothurian Cladolabes schmeltzii, we have found rather complex organization tissue. Transcripts genes encoding wide range structural proteins extracellular matrix, as well various proteases their inhibitors, been discovered. All these molecules may constitute part mechanism According our data, matrix is substantially distinguished from that vertebrates lack elastin, fibronectins, tenascins. case fission, large number transcription factors components different signaling pathways expressed. Products probably involved regulation reproduction, mutability, preparation tissues for subsequent regeneration. It has shown tensilins special group inhibitors metalloproteinases, which formed within class Holothuroidea absent other echinoderms. Our data can serve basis further study responsible