The role of dual energy x-ray absorptiometry in aiding the diagnosis of pediatric osteogenesis imperfecta.

摘要: The role of dual energy x-ray absorptiometry (DEXA) in the evaluation pediatric patient with multiple fractures has not been well established. We retrospectively examined medical records 45 patients who had presented to our institution unknown cause, were known have osteogenesis imperfecta, and obtained DEXA as part their evaluation. Of these, 26 sufficient clinical data for inclusion this study. Patients underwent anteroposterior spine whole body. A z score was calculated normalize values age. diagnosis imperfecta correlated outcome each scan assess validity a diagnostic tool. highest sensitivity at 91.7%, while body specificity 100.0%. Decreased bone mineral density may be associated is helpful detecting low that missed on plain radiographs children milder forms imperfecta.