Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240
作者： T. R. Fenton , D. Nathanson , C. Ponte de Albuquerque , D. Kuga , A. Iwanami
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摘要: … (F) The catalytic activity of recombinant purified GST-tagged PTEN (wild-type or Y240F) … London, United Kingdom) for assistance with bioinformatics. This work was supported by an …
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Paul Kaloudis, Kathrin H. Kirsch, Nikola P. Pavletich, Hidesaburo Hanafusa, Maria-Magdalena Georgescu, Haijuan Yang, Stabilization and Productive Positioning Roles of the C2 Domain of PTEN Tumor Suppressor Cancer Research. ,vol. 60, pp. 7033- 7038 ,(2000)
H-J. Su Huang, Webster K. Cavenee, Frank B. Furnari, The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G1 Growth Arrest in Glioma Cells Cancer Research. ,vol. 58, pp. 5002- 5008 ,(1998)
M K Webster, P Y D'Avis, S C Robertson, D J Donoghue, Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II. Molecular and Cellular Biology. ,vol. 16, pp. 4081- 4087 ,(1996) , 10.1128/MCB.16.8.4081
Shuang-Yin Han, Hideaki Kato, Shunsuke Kato, Takao Suzuki, Hiroyuki Shibata, Seiichi Ishii, Ken-ichi Shiiba, Seiki Matsuno, Ryunosuke Kanamaru, Chikashi Ishioka, None, Functional Evaluation of PTEN Missense Mutations Using in Vitro Phosphoinositide Phosphatase Assay Cancer Research. ,vol. 60, pp. 3147- 3151 ,(2000)
Jie-Oh Lee, Haijuan Yang, Maria-Magdalena Georgescu, Antonio Di Cristofano, Tomohiko Maehama, Yigong Shi, Jack E Dixon, Pier Pandolfi, Nikola P Pavletich, Crystal Structure of the PTEN Tumor Suppressor: Implications for Its Phosphoinositide Phosphatase Activity and Membrane Association Cell. ,vol. 99, pp. 323- 334 ,(1999) , 10.1016/S0092-8674(00)81663-3
J. M. Stommel, A. C. Kimmelman, H. Ying, R. Nabioullin, A. H. Ponugoti, R. Wiedemeyer, A. H. Stegh, J. E. Bradner, K. L. Ligon, C. Brennan, L. Chin, R. A. DePinho, Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies Science. ,vol. 318, pp. 287- 290 ,(2007) , 10.1126/SCIENCE.1142946
Ajay Pandita, Kenneth D. Aldape, Gelareh Zadeh, Abhijit Guha, C. David James, Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR. Genes, Chromosomes and Cancer. ,vol. 39, pp. 29- 36 ,(2004) , 10.1002/GCC.10300
Y. Lindsay, D. McCoull, L. Davidson, N. R. Leslie, A. Fairservice, A. Gray, J. Lucocq, C. P. Downes, Localization of agonist-sensitive PtdIns(3,4,5)P3 reveals a nuclear pool that is insensitive to PTEN expression. Journal of Cell Science. ,vol. 119, pp. 5160- 5168 ,(2006) , 10.1242/JCS.000133
Nicholas Turner, Richard Grose, Fibroblast growth factor signalling: from development to cancer. Nature Reviews Cancer. ,vol. 10, pp. 116- 129 ,(2010) , 10.1038/NRC2780
Kathryn E. Ware, Marianne E. Marshall, Lydia R. Heasley, Lindsay Marek, Trista K. Hinz, Paula Hercule, Barbara A. Helfrich, Robert C. Doebele, Lynn E. Heasley, Rapidly Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in NSCLC Cell Lines through De-Repression of FGFR2 and FGFR3 Expression PLoS ONE. ,vol. 5, pp. e14117- ,(2010) , 10.1371/JOURNAL.PONE.0014117