Effect of suture materials on healing wounds of the stomach and colon.

摘要: Wound healing in the stomach and colon of mongrel dogs was studied using physical, histologic chemical techniques to evaluate effects various suture materials on pattern compare visceral wounds with skin wounds. The general for is same rats, rabbits dogs. However, extent healing, percentage strength normal tissue attained by wound, less dog than rat or rabbit. Prolene plain chromic catgut produce least silk produces greatest cellular reaction colon. We believe effect absorbable sutures wounds, while statistically significant, not any great clinical significance except perhaps severely debilitated patients. A trial anastomotic closure would seem indicated. differs from observed Breaking increases rapidly 14 21 days postwounding then does change significantly. are metabolically more active since rate collagen synthesis markedly elevated even after 120 noncollagenous protein twice as wound it tissue. Colon closed weaker at through 28 similar nonabsorbable sutures. Yet, when expressed a unwounded tissue, there no difference between blosed Thus, appear that diminution wall up 6 centimeters which have been