Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
作者： H. Earl Ruley
DOI: 10.1038/304602A0
关键词:
摘要: The polyoma virus middle-T and the T24 Harvey ras1 genes are individually unable to transform primary baby rat kidney cells. Adenovirus early region 1A provides functions required by these cells following DNA-mediated gene transfer. These results suggest that separate establishment transforming for oncogenic transformation of in culture.
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T Y Shih, M O Weeks, P Gruss, R Dhar, S Oroszlan, E M Scolnick, Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus. Journal of Virology. ,vol. 42, pp. 253- 261 ,(1982) , 10.1128/JVI.42.1.253-261.1982
J R Feramisco, J E Smart, K Burridge, D M Helfman, G P Thomas, Co-existence of Vinculin and a Vinculin-like Protein of Higher Molecular Weight in Smooth Muscle* Journal of Biological Chemistry. ,vol. 257, pp. 11024- 11031 ,(1982) , 10.1016/S0021-9258(18)33927-9
T R Gingeras, D Sciaky, R E Gelinas, J Bing-Dong, C E Yen, M M Kelly, P A Bullock, B L Parsons, K E O'Neill, R J Roberts, Nucleotide sequences from the adenovirus-2 genome. Journal of Biological Chemistry. ,vol. 257, pp. 13475- 13491 ,(1982) , 10.1016/S0021-9258(18)33473-2
Edward M. Scolnick, Wade P. Parks, Harvey Sarcoma Virus: A Second Murine Type C Sarcoma Virus with Rat Genetic Information Journal of Virology. ,vol. 13, pp. 1211- 1219 ,(1974) , 10.1128/JVI.13.6.1211-1219.1974
L. Aiello, R. Guilfoyle, K. Huebner, R. Weinmann, Adenovirus 5 DNA sequences present and RNA sequences transcribed in transformed human embryo kidney cells (HEK-Ad-5 or 293). Virology. ,vol. 94, pp. 460- 469 ,(1979) , 10.1016/0042-6822(79)90476-8
Gerard Goubin, Debra S. Goldman, Judith Luce, Paul E. Neiman, Geoffrey M. Cooper, Molecular cloning and nucleotide sequence of a transforming gene detected by transfection of chicken B-cell lymphoma DNA Nature. ,vol. 302, pp. 114- 119 ,(1983) , 10.1038/302114A0
J. Favaloro, R. Kamen, R. Treisman, U. Novak, Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein Nature. ,vol. 292, pp. 595- 600 ,(1981) , 10.1038/292595A0
Michel Perricaudet, Göran Akusjärvi, Anders Virtanen, Ulf Pettersson, Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses Nature. ,vol. 281, pp. 694- 696 ,(1979) , 10.1038/281694A0
Mitchell Goldfarb, Kenji Shimizu, Manuel Perucho, Michael Wigler, Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells Nature. ,vol. 296, pp. 404- 409 ,(1982) , 10.1038/296404A0
Hartmut Land, Luis F. Parada, Robert A. Weinberg, Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. ,vol. 304, pp. 596- 602 ,(1983) , 10.1038/304596A0