Amphiregulin is a mitogen for adult neural stem cells
作者： Anna Falk , Jonas Frisén
DOI: 10.1002/JNR.10410
关键词:
摘要: Neurons are continuously generated from stem cells in the hippocampus and along lateral ventricles adult brain. Neural can be propagated vitro presence of epidermal growth factor (EGF) or fibroblast factor-2. We report here that amphiregulin, a related to EGF, is mitogen for mouse neural displays potency similar EGF. cell cultures initiated as efficiently amphiregulin only with Furthermore, we show expressed choroid plexus ventricular system brain, suggesting may participate regulation proliferation neurogenesis
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