Reproductive outcomes after assisted conception.

摘要: The last three decades have witnessed a dramatic increase in the use of assisted reproductive technology (ART) so that now, developed countries, 1.7% to 4.0% all children are born after ART. Although absolute risks appear small, data from prospective and retrospective studies indicate increased adverse maternal perinatal outcomes ART as compared with spontaneous conception. Recent suggest underlying factors subfertility play an important role some these rather than procedure itself. A significant risk conception is multiple pregnancies, but even singleton pregnancies achieved by at higher hypertensive disease, diabetes, prematurity, low birth weight, mortality adjusting for confounders. Couples undergoing procedures should be counseled advance regarding pregnancy complications rates obstetric interventions. conflicting exist, congenital malformations, imprinting disorders (Beckwith-Wiedemann syndrome Angelman syndrome), marginally cancer. However, current evidence inadequate, long-term needed eliminate effect confounders draw definite conclusions about remains routine screening not recommended present. difficult evaluate because variability methods reporting, there need standardized methodology follow-up