Clinical validation and risk factors for delayed gastric emptying based on the International Study Group of Pancreatic Surgery (ISGPS) Classification.

作者: Joon Seong Park , Ho Kyoung Hwang , Jae Keun Kim , Sin Il Cho , Dong-Sup Yoon

DOI: 10.1016/J.SURG.2009.05.012

关键词:

摘要: Background Delayed gastric emptying (DGE) is one of the most common complications after pancreatoduodenectomy (PD). Because an objective, universally accepted definition DGE does not yet exist, it impossible to compare complication rates and outcomes new operative approaches, techniques, clinical trials. The International Study Group Pancreatic Surgery (ISGPS) has proposed a universal classification for based on outcomes, but this been tested rigorously applied data. Therefore, aim study was analyze our experience identify predictive factors by applying ISGPS at high-volume hospital. Methods From October 2002 December 2007, 129 consecutive patients underwent PD Department Surgery, Yonsei University Medical Center. severity determined according classification, risk were evaluated retrospectively. Results overall incidence 33.3%, with 16 (12.4%) having grade A, 14 (10.9%) B, 13 (10.1%) C. Clinical worsened progressively as relevant increased. In multivariate analysis, clinically pancreatic fistula (grade B/C) benign pathology identified independent DGE. Conclusion leakage serious also associated clear useful tool assess outcomes.

参考文章(31)
Charles J. Yeo, John L. Cameron, Taylor A. Sohn, Keith D. Lillemoe, Henry A. Pitt, Mark A. Talamini, Ralph H. Hruban, Sarah E. Ord, Patricia K. Sauter, JoAnn Coleman, Marianna L. Zahurak, Louise B. Grochow, Ross A. Abrams, Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Annals of Surgery. ,vol. 226, pp. 248- 260 ,(1997) , 10.1097/00000658-199709000-00004
H. Friess, H. G. Beger, U. Sulkowski, H. Becker, B. Hofbauer, H.-J. Dennler, M. W. Büchler, Randomized controlled multicentre study of the prevention of complications by octreotide in patients undergoing surgery for chronic pancreatitis British Journal of Surgery. ,vol. 82, pp. 1270- 1273 ,(2005) , 10.1002/BJS.1800820938
Charles J. Yeo, M. Kevin Barry, Patricia K. Sauter, Samuel Sostre, Keith D. Lillemoe, Henry A. Pitt, John L. Cameron, Erythromycin accelerates gastric emptying after pancreaticoduodenectomy. A prospective, randomized, placebo-controlled trial. Annals of Surgery. ,vol. 218, pp. 229- 238 ,(1993) , 10.1097/00000658-199309000-00002
Michelle L. DeOliveira, Jordan M. Winter, Markus Schafer, Steven C. Cunningham, John L. Cameron, Charles J. Yeo, Pierre-Alain Clavien, Assessment of complications after pancreatic surgery: A novel grading system applied to 633 patients undergoing pancreaticoduodenectomy. Annals of Surgery. ,vol. 244, pp. 931- 939 ,(2006) , 10.1097/01.SLA.0000246856.03918.9A
Moritz N. Wente, Claudio Bassi, Christos Dervenis, Abe Fingerhut, Dirk J. Gouma, Jakob R. Izbicki, John P. Neoptolemos, Robert T. Padbury, Michael G. Sarr, L. William Traverso, Charles J. Yeo, Markus W. Büchler, Delayed gastric emptying (DGE) after pancreatic surgery: A suggested definition by the International Study Group of Pancreatic Surgery (ISGPS) Surgery. ,vol. 142, pp. 761- 768 ,(2007) , 10.1016/J.SURG.2007.05.005
Susumu Ohwada, Yoshihiro Satoh, Susumu Kawate, Takayuki Yamada, Osamu Kawamura, Toru Koyama, Sumihiko Yoshimura, Naoki Tomizawa, Tetsushi Ogawa, Yasuo Morishita, Low-dose erythromycin reduces delayed gastric emptying and improves gastric motility after Billroth I pylorus-preserving pancreaticoduodenectomy. Annals of Surgery. ,vol. 234, pp. 668- 674 ,(2001) , 10.1097/00000658-200111000-00013
John L. Cameron, Henry A. Pitt, Charles J. Yeo, Keith D. Lillemoe, Howard S. Kaufman, JoAnn Coleman, One hundred and forty-five consecutive pancreaticoduodenectomies without mortality. Annals of Surgery. ,vol. 217, pp. 430- 438 ,(1993) , 10.1097/00000658-199305010-00002
H. Ramesh, C. J. Varghese, P. Pederzoli, C. Bassi, M. Falconi, M. G. Camboni, Efficacy of octreotide in the prevention of complications of elective pancreatic surgery British Journal of Surgery. ,vol. 81, pp. 265- 269 ,(2005) , 10.1002/BJS.1800811146
M. P. Hocking, W. D. Harrison, C. A. Sninsky, Gastric dysrhythmias following pylorus-preserving pancreaticoduodenectomy. Possible mechanism for early delayed gastric emptying. Digestive Diseases and Sciences. ,vol. 35, pp. 1226- 1230 ,(1990) , 10.1007/BF01536411
Andrew M. Lowy, Jeffrey E. Lee, Peter W. T. Pisters, B. Scott Davidson, Claudia J. Fenoglio, Pam Stanford, Rashida Jinnah, Douglas B. Evans, Prospective, randomized trial of octreotide to prevent pancreatic fistula after pancreaticoduodenectomy for malignant disease. Annals of Surgery. ,vol. 226, pp. 632- 641 ,(1997) , 10.1097/00000658-199711000-00008