Doxycycline as a modulator of inflammation in chronic wounds.

摘要:  Doxycycline is a semisynthetic, chemically modified tetracycline compound that rapidly absorbed and exerts biological effects independent of its antimicrobial activity. One such effect includes the inhibition matrix metalloproteinases. has long history as collagenase inhibitor. This article will describe mode action review effectiveness in significantly reducing inflammation elevated levels proinflammatory cytokines within chronic wounds. .