The ultrastructure of platelet pseudopodia and the adhesion of homologous platelets to tumour cells.

摘要: Abstract When homologous platelets in plasma were mixed a Chandler tube apparatus with Walker 256 carcinoma cells and mouse mammary adenocarcinoma tumour-platelet body was formed each case. rat loosely knit corpus of tumour cells, cell debris, activated which showed number pseudopodia contact both intact damaged cells. Mouse denser consisting numerous pseudopodia, fibrin Mixed this mass “balloon” platelets. These pear-shaped profiles single the larger spheroid granule-free smaller granule-rich. No granules seen external to platelet membrane. Platelet took various forms. Single filiform, bifid staghorn types seen. Some originated from microtubular system supported by it. A peripheral bubble containing membranes arranged foamy fashion present at tip some pseudopodia. If leading portion pseudopodium had reached an attractive adhesive surface then it followed for little distance so as result bend away main axis pseudopodium.