Effects of in utero JP-8 jet fuel exposure on the immune systems of pregnant and newborn mice.

摘要: The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding potential effects upon exposed personnel is unclear. Previous work reported that exposure immunosuppressive. In present study, in-utero mice were examined to ascertain any on female and their offspring. Exposure by aerosol route (at 1000 mg/mm3 for 1 h/day; similar exposures incurred flight line personnel) commencing during first (d7 birth) or last (d15 trimester pregnancy was analyzed. It observed even 6–8 weeks after immune system dams (mother newborn mice) affected (in accordance with previous reports normal mice). That is, thymus organ weights viable cell numbers decreased, function depressed. A decrease male offspring found, notably more pron...