CROI 2016: Hot Spots in HIV Infection and Advances in HIV Prevention.

作者: Susan P Buchbinder , Albert Y Liu

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摘要: The 2016 Conference on Retroviruses and Opportunistic Infections (CROI) highlighted hot spots in HIV infection. Men who have sex with men (MSM), transgender populations, people inject drugs, fisherfolk, migrants, adolescents, older adults are heavily impacted a number of regions. Stigma contributes to risk behaviors acquisition across populations. testing is crucial first step the care continuum, several large community-based surveys underway Africa increase testing, linkage care, uptake antiretroviral treatment. Advances preexposure prophylaxis (PrEP) featured prominently at CROI 2016. Two efficacy trials vaginal ring containing investigational drug dapivirine demonstrated safety preventing infections women Africa. Data long-acting injectable PrEP drugs formulations were also presented. Knowledge use among MSM United States appears be increasing, high was seen black when provided as part culturally tailored support program. broadly neutralizing antibodies for prevention novel promising approach evaluated trials.

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