An efficient, scalable patient-derived xenograft system based on a chick chorioallantoic membrane (cam) in vivo model

摘要: Embodiments of the disclosure encompass systems that utilize chick chorioallantoic membranes (CAM) as models for cancer xenografts, including at least patient-derived xenografts (CAM-PDX). In particular embodiments, system employs CAM-PDX to graft and culture different types tumor tissue on a single or multiple eggs. specific embodiments regions are cultured egg. Frozen is successfully revived, in embodiments. Downstream applications following successful establishment encompassed.