Infectious aneurysm of the intracavernous carotid artery occurring concomitantly with sphenoid sinusitis; an autopsy case report

摘要: A previously healthy 56-year-old woman presented with right-sided ophthalmic pain and diplopia following headache fever. neurological examination revealed 3rd 6th right cranial nerve palsies. Brain magnetic resonance imaging (MRI) 3D-computed tomography (CT) angiography (CTA) showed sphenoid sinusitis, cavernous sinus thrombophlebitis, aneurysms in the intracavernous carotid artery a portion of internal carotid-posterior communicating artery. We diagnosed her condition as syndrome an infectious aneurysm secondary to sphenoiditis; therefore, broad spectrum antibiotics were administered. However, 7 days after admission, she died massive epistaxis. Macroscopically, coagulated blood was observed at surface sinus, suggesting bleeding sinus. histopathological severe infiltration inflammatory cells into mucosa. Rupture also observed. no pathogenic organism identified. thought that sinusitis had spread through venous flow cavernous, developed due arterial wall. This is first detailed clinico-pathological study occurring concomitantly sphenoiditis.