From human genome to cancer genome: The first decade

作者: D. A. Wheeler , L. Wang

DOI: 10.1101/GR.157602.113

关键词:

摘要: The realization that cancer progression required the participation of cellular genes provided one several key rationales, in 1986, for embarking on human genome project. Only with a reference sequence could full spectrum somatic changes leading to be understood. Since its completion 2003, has fulfilled promise as foundational tool illuminate pathogenesis cancer. Herein, we review historical milestones genomics since genome, and some novel discoveries are shaping our current understanding

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