Biological encoding of large numbers of cells

作者: Peter Oliver Krutzik , Thomas Scott Wehrman

DOI:

关键词:

摘要: Mixtures of cell types can be analyzed by having at least two signal markers, with one three different levels to provide a barcode for each type. The mixture cells may subjected common candidate moiety and the effect on determined along identification barcode. Conveniently, surface marker proteins labeled antibodies used create flow cytometry.

参考文章(26)
Kenneth R. Schulz, Erika A. Danna, Peter O. Krutzik, Garry P. Nolan, Single-cell phospho-protein analysis by flow cytometry. Current protocols in immunology. ,vol. 96, ,(2007) , 10.1002/0471142735.IM0817S96
Peter O. Krutzik, Garry Nolan, Multiplex Cellular Assays Using Detectable Cell Barcodes ,(2008)
Peter O. Krutzik, Matthew R. Clutter, Garry P. Nolan, Coordinate Analysis of Murine Immune Cell Surface Markers and Intracellular Phosphoproteins by Flow Cytometry Journal of Immunology. ,vol. 175, pp. 2357- 2365 ,(2005) , 10.4049/JIMMUNOL.175.4.2357
Michael C Bibby, Marie Suggitt, 50 Years of Preclinical Anticancer Drug Screening: Empirical to Target-Driven Approaches Clinical Cancer Research. ,vol. 11, pp. 971- 981 ,(2005)
Xing-Dong Feng, Shu-Guang Huang, Jian-Yong Shou, Bi-Rong Liao, Jonathan M. Yingling, Xiang Ye, Xi Lin, Lawrence M. Gelbert, Eric W. Su, Jude E. Onyia, Shu-Yu Li, Analysis of Pathway Activity in Primary Tumors and NCI60 Cell Lines Using Gene Expression Profiling Data Genomics, Proteomics & Bioinformatics. ,vol. 5, pp. 15- 24 ,(2007) , 10.1016/S1672-0229(07)60010-2
L SKLAR, M CARTER, B EDWARDS, Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening. Current Opinion in Pharmacology. ,vol. 7, pp. 527- 534 ,(2007) , 10.1016/J.COPH.2007.06.006
Katherine Williams, Cynthia Chubb, Eliezer Huberman, Carol S. Giometti, Analysis of differential protein expression in normal and neoplastic human breast epithelial cell lines. Electrophoresis. ,vol. 19, pp. 333- 343 ,(1998) , 10.1002/ELPS.1150190231
Peter C. Simons, Susan M. Young, Veronica Gibaja, Wen-Cherng Lee, Serene Josiah, Bruce S. Edwards, Larry A. Sklar, Duplexed, bead-based competitive assay for inhibitors of protein kinases. Cytometry Part A. ,vol. 71, pp. 451- 459 ,(2007) , 10.1002/CYTO.A.20398
Peter O Krutzik, Janelle M Crane, Matthew R Clutter, Garry P Nolan, High-content single-cell drug screening with phosphospecific flow cytometry Nature Chemical Biology. ,vol. 4, pp. 132- 142 ,(2008) , 10.1038/NCHEMBIO.2007.59
Yuelin Zhu, Antai Wang, Minetta Liu, Alan Zwart, Richard Lee, Ann Gallagher, Yue Wang, William Miller, J. Dixon, Robert Clarke, Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures. International Journal of Oncology. ,vol. 29, pp. 1581- 1589 ,(2006) , 10.3892/IJO.29.6.1581