Assessing both genetic variation (SNPs/CNVs) and gene-environment interactions may lead to personalized gastric cancer prevention.

作者: Dimitrios H Roukos

DOI: 10.1586/14737159.9.1.1

关键词:

摘要: Technological advances with next-generation DNA-sequencing and microarrays have revolutionized research on the human genome [1–3]. Three more genomes, including the first one …

参考文章(37)
J. Couzin, Small RNAs Make Big Splash Science. ,vol. 298, pp. 2296- 2297 ,(2002) , 10.1126/SCIENCE.298.5602.2296
Parry Guilford, Justin Hopkins, James Harraway, Maybelle McLeod, Ngahiraka McLeod, Pauline Harawira, Huriana Taite, Robin Scoular, Andrew Miller, Anthony E. Reeve, E-cadherin germline mutations in familial gastric cancer Nature. ,vol. 392, pp. 402- 405 ,(1998) , 10.1038/32918
Manel Esteller, Epigenetics in Cancer The New England Journal of Medicine. ,vol. 358, pp. 1148- 1159 ,(2008) , 10.1056/NEJMRA072067
S. Lilly Zheng, Jielin Sun, Fredrik Wiklund, Shelly Smith, Pär Stattin, Ge Li, Hans-Olov Adami, Fang-Chi Hsu, Yi Zhu, Katarina Bälter, A. Karim Kader, Aubrey R. Turner, Wennuan Liu, Eugene R. Bleecker, Deborah A. Meyers, David Duggan, John D. Carpten, Bao-Li Chang, William B. Isaacs, Jianfeng Xu, Henrik Grönberg, Cumulative Association of Five Genetic Variants with Prostate Cancer The New England Journal of Medicine. ,vol. 358, pp. 910- 919 ,(2008) , 10.1056/NEJMOA075819
Philip R. Taylor, Prevention of Gastric Cancer: A Miss Journal of the National Cancer Institute. ,vol. 99, pp. 101- 103 ,(2007) , 10.1093/JNCI/DJK026
Charles Lee, Cynthia C. Morton, Structural genomic variation and personalized medicine. The New England Journal of Medicine. ,vol. 358, pp. 740- 741 ,(2008) , 10.1056/NEJMCIBR0708452
Douglas F Easton, Karen A Pooley, Alison M Dunning, Paul DP Pharoah, Deborah Thompson, Dennis G Ballinger, Jeffery P Struewing, Jonathan Morrison, Helen Field, Robert Luben, Nicholas Wareham, Shahana Ahmed, Catherine S Healey, Richard Bowman, SEARCH collaborators Luccarini Craig 61 Conroy Don 61 Shah Mitul 61 Munday Hannah 61 Jordan Clare 61 Perkins Barbara 61 West Judy 61 Redman Karen 61 Driver Kristy 61, Kerstin B Meyer, Christopher A Haiman, Laurence K Kolonel, Brian E Henderson, Loic Le Marchand, Paul Brennan, Suleeporn Sangrajrang, Valerie Gaborieau, Fabrice Odefrey, Chen-Yang Shen, Pei-Ei Wu, Hui-Chun Wang, Diana Eccles, D Gareth Evans, Julian Peto, Olivia Fletcher, Nichola Johnson, Sheila Seal, Michael R Stratton, Nazneen Rahman, Georgia Chenevix-Trench, Stig E Bojesen, Børge G Nordestgaard, Christen K Axelsson, Montserrat Garcia-Closas, Louise Brinton, Stephen Chanock, Jolanta Lissowska, Beata Peplonska, Heli Nevanlinna, Rainer Fagerholm, Hannaleena Eerola, Daehee Kang, Keun-Young Yoo, Dong-Young Noh, Sei-Hyun Ahn, David J Hunter, Susan E Hankinson, David G Cox, Per Hall, Sara Wedren, Jianjun Liu, Yen-Ling Low, Natalia Bogdanova, Peter Schürmann, Thilo Dörk, Rob AEM Tollenaar, Catharina E Jacobi, Peter Devilee, Jan GM Klijn, Alice J Sigurdson, Michele M Doody, Bruce H Alexander, Jinghui Zhang, Angela Cox, Ian W Brock, Gordon MacPherson, Malcolm WR Reed, Fergus J Couch, Ellen L Goode, Janet E Olson, Hanne Meijers-Heijboer, Ans van den Ouweland, André Uitterlinden, Fernando Rivadeneira, Roger L Milne, Gloria Ribas, Anna Gonzalez-Neira, Javier Benitez, John L Hopper, Margaret McCredie, Melissa Southey, Graham G Giles, Chris Schroen, Christina Justenhoven, Hiltrud Brauch, Ute Hamann, Yon-Dschun Ko, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, AOCS Management Group Bowtell David 146 Green Adele 82 deFazio Anna 147 Chenevix-Trench Georgia 82 Gertig Dorota 111 Webb Penny 82, Arto Mannermaa, Veli-Matti Kosma, Vesa Kataja, Jaana Hartikainen, Nicholas E Day, David R Cox, Bruce AJ Ponder, None, Genome-wide association study identifies novel breast cancer susceptibility loci Nature. ,vol. 447, pp. 1087- 1093 ,(2007) , 10.1038/NATURE05887
David Forman, Paola Pisani, Gastric Cancer in Japan — Honing Treatment, Seeking Causes The New England Journal of Medicine. ,vol. 359, pp. 448- 451 ,(2008) , 10.1056/NEJMP0804354
Stephen J Chanock, Teri Manolio, Michael Boehnke, Eric Boerwinkle, David J Hunter, Gilles Thomas, Joel N Hirschhorn, Gonçalo R Abecasis, David Altshuler, Joan E Bailey-Wilson, Lisa D Brooks, Lon R Cardon, Mark Daly, Peter Donnelly, Joseph F Fraumeni Jr, Nelson B Freimer, Daniela S Gerhard, Chris Gunter, Alan E Guttmacher, Mark S Guyer, Emily L Harris, Josephine Hoh, Robert Hoover, C Augustine Kong, Kathleen R Merikangas, Cynthia C Morton, Lyle J Palmer, Elizabeth G Phimister, John P Rice, Jerry Roberts, Charles Rotimi, Margaret A Tucker, Kyle J Vogan, Sholom Wacholder, Ellen M Wijsman, Deborah M Winn, Francis S Collins, Replicating genotype–phenotype associations Nature. ,vol. 447, pp. 655- 660 ,(2007) , 10.1038/447655A