Association of blood bicarbonate and pH with mineral metabolism disturbance and outcome after kidney transplantation.

摘要: In kidney transplant recipients (KTRs), scarce evidence has associated low blood bicarbonate levels with mineral metabolic disturbance and reduced allograft survival. However, the contribution of pH to these observations remains unassessed. Equally, little is known about influence provenance (arteriovenous fistula vs peripheral vein) on values. We analyzed gas parameters in a single-center cohort 1260 stable KTRs, 3 months after transplantation. Inspection pO2 distribution allowed unambiguous identification arterial (N = 914) or venous 346) origin samples. patients samples, 435 (46%) had below 22 mmol/L. Among them, 196 (40%) were acidemic (blood <7.38). multivariate analysis, was increased ionized calcium phosphate fibroblast growth factor 23 calcitriol, but not outcome. contrast, concentration predicted loss independently measured glomerular filtration rate other potential confounders (hazard ratio [HR] 1.70; 95% confidence interval [CI] 1.04-2.80). predict outcome while acidemia altered metabolism.