Post-eradication poliovirus facility-associated community risks

摘要: Minimizing the risk of poliovirus transmission from facility to an increasingly susceptible community is crucial when global and OPV use stops. Community risks exposure wild as well Sabin strains are highest personnel who unknowingly contaminated or infected. Immunization with IPV prevents poliomyelitis, but neither vaccine fully inhibits silent infection gut. Facility environments maintained at low relative humidity (<50%) may reduce survival inhalation risk. Circulating antibodies injection virus entry through breaks in skin mucous membranes. air effluent likely most modern facilities. ingestion liquid effluents facility-specific range high low. This assessment risks, combined assessments hazards consequences transmission, provides foundation for effective management.