摘要: … The intercellular spaces between intestinal epithelials become wide (existence of leaky gut) in T1D, due to zonulin upregulation and tight junction-related gene downregulation. The …
Mikael Knip, Suvi M. Virtanen, Karri Seppä, Jorma Ilonen, Erkki Savilahti, Outi Vaarala, Antti Reunanen, Kari Teramo, Anu-Maaria Hämäläinen, Johanna Paronen, Hans-Michael Dosch, Timo Hakulinen, Hans K. Åkerblom, Dietary intervention in infancy and later signs of beta-cell autoimmunity.The New England Journal of Medicine. ,vol. 363, pp. 1900- 1908 ,(2010) , 10.1056/NEJMOA1004809