H3-THYMIDINE DERIVATIVE POOLS IN RELATION TO MACRONUCLEAR DNA SYNTHESIS IN TETRAHYMENA PYRIFORMIS

摘要: The formation of a soluble H3-thymidine derivative pool has been examined in Tetrahymena pyriformis as function macronuclear DNA synthesis during the cell life cycle. An autoradiographic technique which allows detection water-soluble materials within shown that these cells do not take up and retain exogenous G1 or G2. Uptake is restricted to S period Additional experiments show, however, derivatives persists from end one beginning next subsequent Since this persisting cannot be labeled with H3-thymidine, does turn over non-S periods.