A gene regulatory network simulation of heterosis

摘要: We describe a simulation of multi-genic heterosis using Boolean gene regulatory networks. Hybrid vigor, or heterosis, is the phenomenon whereby offspring crosses from separate populations often perform better than inbreds with respect to growth rate, fertility and disease resistance. Because its great economic importance, genetic molecular basis has been subject many scientific studies. However, attempts model systems biology point view have quite abstract. Our allows generation, evolution, homologous recombination hybridisation networks which display properties observed in simulated environment. can thus test current hypotheses about investigate factors affect it.