作者: Matthew B. Nodwell , Stephan A. Sieber
DOI: 10.1007/128_2011_302
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摘要: Activity-based protein profiling (ABPP) is emerging as a mature method for chemically interrogating the proteome of cell. This chapter serves to introduce reader ABPP by providing overviews general principles technique, analytical methods used in ABPP, classes enzymes that can be specifically addressed probes, and biological applications ABPP.