Individualization of cancer treatment: contribution of OMICs technologies to cancer diagnostic

摘要: Cancer still kills people. It was easier to send a man in the outer space or Moon, than improve survival of patients having advanced and metastatic cancers. This highlights complexity cancer as disease, which is apparently much higher build launch rocket. Carcinogenic transformation cells accepted main cause [1–4]. defined number changes cell physiology, lead expansion malignant body, corrupting normal ultimately killing person. The key conclusion more 50 years intense studies that collected knowledge has not reached critical mass required find cure against cancer. oncogenes tumor suppressor model been great step forward [1–4], but today clear carcinogenic result interaction hundreds molecules. Out these cancer-promoting genes, RNAs, proteins metabolites many are same they cells. their corrupted activity, mis-localization, misplaced interactions make them tumorpromoting (Fig. 1). confusion only underlined A solution problem proposed by introduction technologies for comprehensive study carcinogenesis. These focused on genomic DNA (genomics), RNAs (transcripUDK 575.113+577.214+612.321