Early life stages of Northern shrimp (Pandalus borealis) are sensitive to fish feed containing the anti-parasitic drug diflubenzuron

摘要: Abstract Increasing use of fish feed containing the chitin synthesis inhibiting anti-parasitic drug diflubenzuron (DFB) in salmon aquaculture has raised concerns over its impact on coastal ecosystems. Larvae Northern shrimp (Pandalus borealis) were exposed to DFB medicated under Control conditions (7.0 °C, pH 8.0) and Ocean Acidification Warming (OAW, 9.5 °C 7.6). Two weeks’ exposure caused significantly increased mortality. The effect OAW mortality larvae was additive; 10% Control, 35% OAW, 66% 92% OAW + DFB. In OAW + DFB feeding swimming activity reduced for stage II none surviving developed IV. genes involved (GAPDH PRLP) one gene moulting (DD9B) downregulated relative Control. Due a shorter intermoult period conditions, throughout two instead critical pre-moult period. This may explain more serious sub-lethal effects than larvae. A single day at 4 days after hatching did not affect larvae, but high observed possibly because they closer moulting. High feed, indicates that is threat crustacean zooplankton.