A Clinical Decision Support System Using Ultrasound Textures and Radiologic Features to Distinguish Metastasis From Tumor-Free Cervical Lymph Nodes in Patients With Papillary Thyroid Carcinoma.

作者: Ali Abbasian Ardakani , Reza Reiazi , Afshin Mohammadi

DOI: 10.1002/JUM.14610

关键词:

摘要: Objectives This study investigated the potential of a clinical decision support approach for classification metastatic and tumor-free cervical lymph nodes (LNs) in papillary thyroid carcinoma on basis radiologic textural analysis through ultrasound (US) imaging. Methods In this research, 170 LNs were examined by proposed method. To discover difference between groups, US imaging was used extraction features. The features B-mode scans included echogenicity, margin, shape, presence microcalcification. extract features, wavelet transform applied. A vector machine classifier to classify LNs. Results training set data, combination represented best performance with sensitivity, specificity, accuracy, area under curve (AUC) values 97.14%, 98.57%, 97.86%, 0.994, respectively, whereas based alone yielded lower performance, AUCs 0.964 0.922. On testing data set, model could an AUC 0.952, which corresponded accuracy 93.33%, 96.66%, 95.00%. Conclusions method has characterize via 2-dimensional US. Therefore, it can be as supplementary technique daily practice improve radiologists' understanding conventional characterizing

参考文章(31)
Aneta Chmielewski, Paul Dufort, Anabel M. Scaranelo, A Computerized System to Assess Axillary Lymph Node Malignancy from Sonographic Images Ultrasound in Medicine & Biology. ,vol. 41, pp. 2690- 2699 ,(2015) , 10.1016/J.ULTRASMEDBIO.2015.05.022
Cristina Dudau, Shema Hameed, Daren Gibson, Senthil Muthu, Ann Sandison, Rob J. Eckersley, Peter Clarke, David O. Cosgrove, Adrian K. Lim, Can Contrast-Enhanced Ultrasound Distinguish Malignant from Reactive Lymph Nodes in Patients with Head and Neck Cancers? Ultrasound in Medicine and Biology. ,vol. 40, pp. 747- 754 ,(2014) , 10.1016/J.ULTRASMEDBIO.2013.10.015
J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, X. Li, Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues Ultrasonic Imaging. ,vol. 13, pp. 111- 134 ,(1991) , 10.1177/016173469101300201
Yoon Jung Choi, Ji Sup Yun, Shin Ho Kook, Eun Choel Jung, Yong Lai Park, Clinical and Imaging Assessment of Cervical Lymph Node Metastasis in Papillary Thyroid Carcinomas World Journal of Surgery. ,vol. 34, pp. 1494- 1499 ,(2010) , 10.1007/S00268-010-0541-1
Chuan-Yu Chang, Chih-Chin Lai, Cheng-Ting Lai, Shao-Jer Chen, Integrating PSONN and Boltzmann function for feature selection and classification of lymph nodes in ultrasound images Journal of Visual Communication and Image Representation. ,vol. 24, pp. 23- 30 ,(2013) , 10.1016/J.JVCIR.2012.10.004
Louise Davies, H. Gilbert Welch, Current Thyroid Cancer Trends in the United States Archives of Otolaryngology-head & Neck Surgery. ,vol. 140, pp. 317- 322 ,(2014) , 10.1001/JAMAOTO.2014.1
Shao-Jer Chen, Chun-Hung Lin, Chuan-Yu Chang, Ku-Yaw Chang, Hsu-Chueh Ho, Shih-Hsuan Hsiao, Chih-Wen Lin, Jeh-En Tzeng, Yen-Ting Chen, Hong-Ming Tsai, Characterizing the major sonographic textural difference between metastatic and common benign lymph nodes using support vector machine with histopathologic correlation Clinical Imaging. ,vol. 36, pp. 353- 359.e2 ,(2012) , 10.1016/J.CLINIMAG.2011.10.018
Corinna Cortes, Vladimir Vapnik, Support-Vector Networks Machine Learning. ,vol. 20, pp. 273- 297 ,(1995) , 10.1023/A:1022627411411
Junhua Zhang, Yuanyuan Wang, Yi Dong, Yi Wang, Computer-aided diagnosis of cervical lymph nodes on ultrasonography Computers in Biology and Medicine. ,vol. 38, pp. 234- 243 ,(2008) , 10.1016/J.COMPBIOMED.2007.10.005
Jong Ju Jeong, Yong Sang Lee, Seung Chul Lee, Sang-Wook Kang, Woong Youn Chung, Hang-Seok Chang, Won Youl Seo, Ki Jun Song, Cheong Soo Park, A scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer. Journal of Korean Medical Science. ,vol. 26, pp. 996- 1000 ,(2011) , 10.3346/JKMS.2011.26.8.996