Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage.

作者: M M Slupska , C Baikalov , W M Luther , J H Chiang , Y F Wei

DOI: 10.1128/JB.178.13.3885-3892.1996

关键词:

摘要: … the repair of oxidative damage to DNA and helps to prevent mutations from oxidative lesions… For sequencing cDNA clones, we employed PCR conditions described by the manufacturer; …

参考文章(19)
Mark D Adams, Anthony R Kerlavage, Robert D Fleischmann, Rebecca A Fuldner, Carol J Bult, Norman H Lee, Ewen F Kirkness, Keith G Weinstock, Jeannine D Gocayne, Owen White, None, Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. Nature. ,vol. 377, pp. 3- 174 ,(1995)
Jeffrey H. Miller, A short course in bacterial genetics ,(1992)
Lawrence A. Loeb, Mutator Phenotype May Be Required for Multistage Carcinogenesis Cancer Research. ,vol. 51, pp. 3075- 3079 ,(1991)
K Sakumi, M Furuichi, T Tsuzuki, T Kakuma, S Kawabata, H Maki, M Sekiguchi, Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis. Journal of Biological Chemistry. ,vol. 268, pp. 23524- 23530 ,(1993) , 10.1016/S0021-9258(19)49494-5
Lawrence A. Loeb, Microsatellite Instability: Marker of a Mutator Phenotype in Cancer Cancer Research. ,vol. 54, pp. 5059- 5063 ,(1994)
Richard Fishel, Mary Kay Lescoe, M.R.S. Rao, Neal G. Copeland, Nancy A. Jenkins, Judy Garber, Michael Kane, Richard Kolodner, The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer Cell. ,vol. 75, pp. 1027- 1038 ,(1993) , 10.1016/0092-8674(93)90546-3
Hisaji Maki, Mutsuo Sekiguchi, Mutt protein specifically hydrolyses a potent mutagenic substrate for dna synthesis Nature. ,vol. 355, pp. 273- 275 ,(1992) , 10.1038/355273A0
Paul Modrich, Mechanisms and biological effects of mismatch repair. Annual Review of Genetics. ,vol. 25, pp. 229- 253 ,(1991) , 10.1146/ANNUREV.GE.25.120191.001305
C. Eric Bronner, Sean M. Baker, Paul T. Morrison, Gwynedd Warren, Leslie G. Smith, Mary Kay Lescoe, Michael Kane, Christine Earabino, James Lipford, Annika Lindblom, Pia Tannergård, Roni J. Bollag, Alan R. Godwin, David C. Ward, Magnus Nordenskj⊘ld, Richard Fishel, Richard Kolodner, R. Michael Liskay, Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer Nature. ,vol. 368, pp. 258- 261 ,(1994) , 10.1038/368258A0
Y. Nghiem, M. Cabrera, C. G. Cupples, J. H. Miller, The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions Proceedings of the National Academy of Sciences of the United States of America. ,vol. 85, pp. 2709- 2713 ,(1988) , 10.1073/PNAS.85.8.2709