作者: J. Gregor Sutcliffe , Brian S. Hilbush
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摘要: The present invention relates to methods and compositions for modulating levels of amyloid-β peptide (Aβ) exhibited by non-neuronal (i.e., peripheral) cells, fluids, or tissues. also modulation Aβ via selective (e.g., inhibition) γ-secretase activity. preventing, treating ameliorating the symptoms a disorder, including but not limited an Aβ-related administering compound that results in tissue, either directly indirectly prevent, treat ameliorate brain such as Alzheimer's disease.