Drug transfer and metabolism by the human placenta

作者: Michael R Syme , James W Paxton , Jeffrey A Keelan

DOI: 10.2165/00003088-200443080-00001

关键词:

摘要: The major function of the placenta is to transfer nutrients and oxygen from the mother to the foetus and to assist in the removal of waste products from the foetus to the mother. In …

参考文章(258)
Alan M. Munk, Transfer of drugs The Journal of the American Dental Association. ,vol. 110, pp. 876- ,(1985) , 10.14219/JADA.ARCHIVE.1985.0006
R D Boyd, C Haworth, T E Stacey, H T Ward, Permeability of the sheep placenta to unmetabolized polar non-electrolytes. The Journal of Physiology. ,vol. 256, pp. 617- 634 ,(1976) , 10.1113/JPHYSIOL.1976.SP011342
Jukka Hakkola, Markku Pasanen, Janne Hukkanen, Olavi Pelkonen, Jukka Mäenpää, Robert J. Edwards, Alan R. Boobis, Hannu Raunio, Expression of xenobiotic-metabolizing cytochrome P450 Forms in human full-term placenta Biochemical Pharmacology. ,vol. 51, pp. 403- 411 ,(1996) , 10.1016/0006-2952(95)02184-1
Jukka Hakkola, Hannu Raunio, Raija Purkunen, Olavi Pelkonen, Seppo Saarikoski, Thierry Cresteil, Markku Pasanen, Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy Biochemical Pharmacology. ,vol. 52, pp. 379- 383 ,(1996) , 10.1016/0006-2952(96)00216-X
George I. Henderson, Zhie Q. Hu, Y. Yang, Tony B. Perez, Bheemappa G. Devi, Teri A. Frosto, Steven Schenker, Ganciclovir Transfer by Human Placenta and Its Effects on Rat Fetal Cells The American Journal of the Medical Sciences. ,vol. 306, pp. 151- 156 ,(1993) , 10.1097/00000441-199309000-00004
M. Bonati, R. Bortolus, F. Marchetti, M. Romero, G. Tognoni, Drug use in pregnancy: an overview of epidemiological (drug utilization) studies European Journal of Clinical Pharmacology. ,vol. 38, pp. 325- 328 ,(1990) , 10.1007/BF00315569
Xiang Wu, Puttur D. Prasad, Frederick H. Leibach, Vadivel Ganapathy, cDNA Sequence, Transport Function, and Genomic Organization of Human OCTN2, a New Member of the Organic Cation Transporter Family Biochemical and Biophysical Research Communications. ,vol. 246, pp. 589- 595 ,(1998) , 10.1006/BBRC.1998.8669
T.I. Ala-Kokko, P. Myllynen, K. Vähäkangas, Ex vivo perfusion of the human placental cotyledon: implications for anesthetic pharmacology International Journal of Obstetric Anesthesia. ,vol. 9, pp. 26- 38 ,(2000) , 10.1054/IJOA.1999.0312
Phillip Nieburg, James S Marks, Nancy M McLaren, Patrick L Remington, The Fetal Tobacco Syndrome JAMA: The Journal of the American Medical Association. ,vol. 253, pp. 2998- 2999 ,(1985) , 10.1001/JAMA.1985.03350440076035