Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation
作者： Antonia A. Dominguez , Wendell A. Lim , Lei S. Qi
DOI: 10.1038/NRM.2015.2
关键词:
摘要: … dCas9–VP64, further increased endogenous gene activation compared with dCas9–VP64 … VPR is a complex of VP64, p65AD and Epstein–Barr virus R transactivator Rta) and a mixed …
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Scot A. Wolfe, Lena Nekludova, Carl O. Pabo, DNA recognition by Cys2His2 zinc finger proteins. Annual Review of Biophysics and Biomolecular Structure. ,vol. 29, pp. 183- 212 ,(2000) , 10.1146/ANNUREV.BIOPHYS.29.1.183
Diego Balboa, Jere Weltner, Solja Eurola, Ras Trokovic, Kirmo Wartiovaara, Timo Otonkoski, Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation Stem cell reports. ,vol. 5, pp. 448- 459 ,(2015) , 10.1016/J.STEMCR.2015.08.001
Catherine E. Ovitt, Hans R. Schöler, Alexander Brehm, Michael Gross, Guy Fuhrmann, Karin Hübner, Young Il Yeom, Kazuyuki Ohbo, Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells Development. ,vol. 122, pp. 881- 894 ,(1996) , 10.1242/DEV.122.3.881
Martin Kampmann, Max A. Horlbeck, Yuwen Chen, Jordan C. Tsai, Michael C. Bassik, Luke A. Gilbert, Jacqueline E. Villalta, S. Chul Kwon, Hyeshik Chang, V. Narry Kim, Jonathan S. Weissman, Next-generation libraries for robust RNA interference-based genome-wide screens. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 112, pp. 201508821- ,(2015) , 10.1073/PNAS.1508821112
Ami M. Kabadi, Charles A. Gersbach, Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression Methods. ,vol. 69, pp. 188- 197 ,(2014) , 10.1016/J.YMETH.2014.06.014
Randall J. Platt, Sidi Chen, Yang Zhou, Michael J. Yim, Lukasz Swiech, Hannah R. Kempton, James E. Dahlman, Oren Parnas, Thomas M. Eisenhaure, Marko Jovanovic, Daniel B. Graham, Siddharth Jhunjhunwala, Matthias Heidenreich, Ramnik J. Xavier, Robert Langer, Daniel G. Anderson, Nir Hacohen, Aviv Regev, Guoping Feng, Phillip A. Sharp, Feng Zhang, CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling Cell. ,vol. 159, pp. 440- 455 ,(2014) , 10.1016/J.CELL.2014.09.014
Ophir Shalem, Neville E. Sanjana, Ella Hartenian, Xi Shi, David A. Scott, Tarjei S. Mikkelsen, Dirk Heckl, Benjamin L. Ebert, David E. Root, John G. Doench, Feng Zhang, Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells Science. ,vol. 343, pp. 84- 87 ,(2014) , 10.1126/SCIENCE.1247005
Woong Y Hwang, Yanfang Fu, Deepak Reyon, Morgan L Maeder, Shengdar Q Tsai, Jeffry D Sander, Randall T Peterson, J-R Joanna Yeh, J Keith Joung, Efficient genome editing in zebrafish using a CRISPR-Cas system Nature Biotechnology. ,vol. 31, pp. 227- 229 ,(2013) , 10.1038/NBT.2501
Josiane E. Garneau, Marie-Ève Dupuis, Manuela Villion, Dennis A. Romero, Rodolphe Barrangou, Patrick Boyaval, Christophe Fremaux, Philippe Horvath, Alfonso H. Magadán, Sylvain Moineau, The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA. Nature. ,vol. 468, pp. 67- 71 ,(2010) , 10.1038/NATURE09523
Yuyu Niu, Bin Shen, Yiqiang Cui, Yongchang Chen, Jianying Wang, Lei Wang, Yu Kang, Xiaoyang Zhao, Wei Si, Wei Li, Andy Peng Xiang, Jiankui Zhou, Xuejiang Guo, Ye Bi, Chenyang Si, Bian Hu, Guoying Dong, Hong Wang, Zuomin Zhou, Tianqing Li, Tao Tan, Xiuqiong Pu, Fang Wang, Shaohui Ji, Qi Zhou, Xingxu Huang, Weizhi Ji, Jiahao Sha, Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos Cell. ,vol. 156, pp. 836- 843 ,(2014) , 10.1016/J.CELL.2014.01.027