Amyloidosis of the liver on shear wave elastography: case report and review of literature
作者： Dmitry S. Trifanov , Manish Dhyani , Jacob R. Bledsoe , Joseph Misdraji , Atul K. Bhan
DOI: 10.1007/S00261-015-0519-4
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摘要: Amyloidosis is extremely rare, with an estimated 2225 new US cases reported annually. Signs and symptoms of the disease are subtle imaging findings not pathognomonic. Currently, diagnosis requires biopsy to demonstrate deposition amyloid. Elastography a modality that evaluates tissue elasticity. It has shown have efficacy in characterizing thyroid nodules, detecting prostate cancer, staging liver fibrosis. We present case hepatic amyloidosis 51-year-old male demonstrates significantly increased stiffness median value 99.1 kPa (range 25.7–188.9 kPa) on shear-wave elastography (SWE) imaging, which higher than the cut-off range for cirrhosis SWE (10.4–11.5 kPa). This finding raises possibility elastographic may be sensitive mechanical changes induced by amyloid deposition.
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