NGSANE: A Lightweight Production Informatics Framework for High Throughput Data Analysis

摘要: Summary: The initial steps in the analysis of next-generation sequencing data can be automated by way software ‘pipelines’. However, individual components depreciate rapidly because evolving technology and methods, often rendering entire versions production informatics pipelines obsolete. Constructing from Linux bash commands enables use hot swappable modular as opposed to more rigid program call wrapping higher level languages, implemented comparable published pipelining systems. Here we present Next Generation Sequencing ANalysis for Enterprises (NGSANE), a Linux-based, high-performance-computing-enabled framework that minimizes overhead set up processing new projects, yet maintains full flexibility custom scripting when raw sequence data. Availability implementation: Ngsane is publicly available under BSD (3-Clause) licence via GitHub at https://github.com/BauerLab/ngsane. Contact: ua.orisc@reuaB.sineD Supplementary information: Supplementary are Bioinformatics online.